Championship side Oxford United beat League Two's MK Dons on penalties after their match ended 1-1, while a couple of League One teams moved on, with Wigan Athletic beating Championship side Preston North End 1-0, and Port Vale defeating League Two's Fleetwood Town 1-0.
Holders Bayern Munich beat Bayer Leverkusen 5-3 on penalties after a 0-0 draw to move into the German Cup semi-final and stay on course for a treble of titles on Wednesday.
Bayern Munich slumped out of the German Cup semi-finals 2-0 on penalties to Borussia Dortmund.
City forward Erling Haaland, who had missed a first-half penalty, made amends in the 57th minute
From Royal Challengers Bengaluru's historic first IPL title to star javelin thrower Neeraj Chopra finally breaking the iconic 90-meter mark to India women winning their first cricket World Cup, this was the year of long-awaited victories and record-breaking feats.
Real Madrid will play local rivals Atletico Madrid while Bayern Munich were drawn against Bundesliga title challengers Bayer Leverkusen on Friday.
IMAGES from the UEFA Champions League matches played on Wednesday
Real have not lost any of their last six games against Liverpool in the Champions League
Holders Bayern Munich struck either side of the break to beat second division Eintracht Braunschweig 2-0 on Wednesday and advance to the German Cup quarter-finals.
Reigning champions Inter Milan will bid to overcome a 1-0 deficit when they face Bayern Munich in their Champions League round of 16 second leg on Tuesday.
Holders Real Madrid will play 2021 winners Chelsea in the Champions League quarter-finals while Manchester City's Pep Guardiola will visit his former club Bayern Munich.
Real Madrid beat holders Manchester City in an edge-of-your-seat 4-3 shootout victory to reach the semi-finals of the Champions League.
Holders Bayern Munich eased into the German Cup third round with a comfortable 3-1 win at Hamburg SV on Wednesday to continue their unbeaten domestic run as they prepare for Saturday's league clash against Borussia Dortmund.
Images from the Champions League matches played across Europe on Tuesday.
Cristiano Ronaldo became the first player to score 100 goals in UEFA competitions when he struck twice as holders Real Madrid came from behind to win 2-1 at Bayern Munich in the first leg of their Champions League quarter-final on Wednesday.
'We've been talking during this week and now it's the right moment to announce it.'
Mouth-watering matches lined up as PSG to face Bayern and Barcelona in Champions League opening stage.
Bayern Munich gained some revenge for their 2012 Champions League final defeat by Chelsea when they beat the Premier League club 5-4 on penalties after a thrilling UEFA Super Cup ended 2-2 at the end of extra-time on Friday.
Images from Wednesday's action in the Champions League.
Bayern Munich striker Robert Lewandowski netted the Bundesliga's fastest hat-trick on his way to a sensational five-goal haul as a halftime substitute in their 5-1 demolition of VfL Wolfsburg on Tuesday.
Real Madrid coach Carlo Ancelotti praised his team for beating holders Bayern Munich in Wednesday's Champions League semi-final, first leg without their two biggest names taking a leading role.
Holders Real Madrid came from a goal down to snatch a precious 2-1 victory at wasteful Bayern Munich on Wednesday and carry a considerable advantage into their Champions League semi-final second leg in Spain.
Cristiano Ronaldo's hat-trick for Real Madrid illuminated an opening night goals bonanza as the leading contenders began the Champions League group stage with a bang on Tuesday.
Real Madrid's world record signing Gareth Bale looked forward to his first Champions League final after a 4-0 thrashing of holders Bayern Munich on Tuesday and said it was exactly why he wanted to join the Spanish side.
Manuel Pellegrini's record against Pep Guardiola is a sorry one but he gets another chance to finally put one over his tormentor when Manchester City host holders Bayern Munich in the Champions League on Wednesday.
IMAGES from Champions League matches played on Tuesday.
Paris St Germain reached the Champions League semi-finals despite a 1-0 home defeat by holders Bayern Munich as they progressed on away goals
Holders Real Madrid reached the Champions League final for a third year in a row after taking advantage of Bayern Munich's carelessness in attack and defence to draw 2-2 in their semi-final second leg on Tuesday, and winning 4-3 on aggregate, at the Santiago Bernabeu, in Madrid, Spain, on Tuesday.
The Bavarians advanced to the German Cup last four after eliminating holders Dortmund, who had also won back-to-back league titles in 2011 and 2012, with a sparkling performance.
Bayern Munich defender Jerome Boateng returned to haunt his former club with a last-gasp goal that secured a 1-0 win over English title holders Manchester City in their opening Champions League Group E clash on Wednesday.
The following is the draw for the Champions League last 16 which was held in Nyon on Monday:
Bayern Munich winger Franck Ribery is out of the Champions League last-16 first leg at Arsenal on February 19 after having an operation on burst blood vessels in his buttocks.
Arsenal will have another chance to beat Bayern Munich in a Champions League knockout tie after the sides were paired in the round of 16 following Monday's draw. The teams met in the knockout stages in 2005, 2013 and 2014 with the German champions winning on all three occasions. Bayern, who finished as runners-up in their group, will host the first leg.
German champions Bayern Munich clinched the German Cup with a crushing 4-0 win over holders Werder Bremen on Saturday to stay on track for a treble. Bayern, who face Inter Milan in the Champions League final on May 22, took the lead through Arjen Robben's first half penalty before Ivica Olic doubled their lead in the 51st minute. Franck Ribery and Bastian Schweinsteiger added two more to cap a memorable domestic season for Bayern.
Chelsea survived the dismissal of captain John Terry to eliminate holders Barcelona 3-2 on aggregate and clinch a place in the Champions League final after an action-packed last-four clash on Tuesday in which Lionel Messi missed a penalty.
Holders Barcelona and Bayern Munich reached the Champions League semi-finals with home wins over AC Milan and Olympique Marseille respectively on Tuesday as Lionel Messi broke another record with his 13th and 14th goals of this season's competition.
Manchester City's memorable Champions League win over holders Bayern Munich still failed to add up for manager Manuel Pellegrini after he revealed his poor grasp of simple mathematics.
Real Madrid struck early through Karim Benzema and comfortably held Bayern Munich at bay to beat the holders 1-0 on Wednesday and move a step closer to a first Champions League final in 12 years.
A first-half penalty earned Lille a shock 1-0 home victory over holders Real Madrid in the Champions League group phase on Wednesday.
Holders Bayern Munich eased past CSKA Moscow 3-1 on Wednesday to set a Champions League record with their 10th straight victory and underline their ambitions to become the first team to successfully defend the title.